Intracytoplasmic Sperm Injection

Intracytoplasmic Sperm Injection (ICSI)

What is ICSI?

ICSI is an assisted reproductive technology in which sperm is injected directly into the egg therefore also known as intracytoplasmic sperm injection. It uses specialized micromanipulation tools and equipments.

How is ICSI Done?

All steps for stimulation of ovaries and egg retrieval procedure are same as IVF. After the granulosa cells have been stripped away from oocyte with enzymatic action the oocyte is held in place by a holding pipette. A single selected sperm is first immobilized and then drawn into the pipette carrying sperm pierces the oocyte wall and sperm injected directly into the ooplasm. The morning after insemination the eggs are examined to determine whether fertilization has occurred.

You do ICSI in which cases?

ICSI is done when male factor is associated with infertility. The indications of ICSI are :

  • Oligospermia – Less than 5 million sperms / ml
  • Asthenospermia – less than 5% progressive motility
  • Teratospermia – less than 4 % normal form
  • When using surgically retrieved sperms
  • Previous failed fertilization with IVF
  • Low yield of eggs at egg retrieval

Are ICSI babies normal?

Prenatal outcome studies suggest that there is no evidence of increased risk of congenital malformation in babies born of IVF/ICSI

Is Ovulation induction done in normal ovulation women also?

Though same ovulation drugs are used in normal ovulation women but it is known as controlled ovarian hyper stimulation.

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