Importance of Genetic testing (PGT) of embryos for abnormalities

Our breakthrough is preimplantation genetic screening (PGT-A) of embryos for abnormalities.

#PGT offers voluble insights into the genetic composition of embryos

Helping couples make informed decisions & significantly improving the chances of a successful pregnancy.

#Here we will explore the importance of genetic testing (PGT) of embryos for abnormalities & its numerous benefits

(PGT)

(PREIMPLANTATION GENETIC SCREENING ) / TESTING

It allows the selection of embryos with the highest likelihood of developing into the healthy pregnancies by screening for chromosomal abnormalities.

Detecting Genetic Abnormalities:-

It enables the identification of chromosomal abnormalities such as aneuploidy or structural rearrangements.This information helps determine the viability and health of embryos before they are transferred into the uterus.

Reducing the Risk of Genetic Disorder:-

Improving Success Rates of Assisted Reproductive :- By selecting embryos with the correct number of structure of chromosomes, PGT enhances the success rates of assisted reproductive technologies. (ART) such as an IVF.

Ethical Considerations Includes:

Handling of excess embryos

Psychological impact of screening for certain conditions

Embryo Biopsy	Genetic Testing Methods	Result Analysis
Few cells are carefully extracted from each embryo for genetic testing.	Includes (NGS) Next generation sequencing or (PCR).
Occurs on 3rd day after fertilization or during blastocyst stage.

Day 3 Embryo Biopsy

Day 5 Embryo Biopsy

PGT Limitations

Its important to acknowledge its limitations:

PGT does not guarantee the birth of a healthy baby, as it cannot detect all genetic abnormalities or address mom – genetic factors that may affect pregnancy.

So, there is still 1% risk of abnormalities in baby.
False +VE or False –VE results can occur, leading to incorrect interpretations of embryo viability.