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Ovarian Rejuvenation

Ovarian Rejuvenation

Revolution in the medical sciences provides a chance to women to revitalize their ovaries by a therapy called ovarian rejuvenation. The therapy offers hope to those patients who have problems like low Oocyte reserve, premature ovarian failure, early menopause problems, and Anti-Mullerian hormone levels.

It is a fact that, a woman is born with millions of Oocyte in her ovaries and as she grows up the egg supply declines in number and in quality as well. It seems quite impossible to develop new eggs in the ovaries naturally. But, according to the recent researches, it is possible to regenerate new eggs with the help of patient’s blood cells. Blood cells have growth factors which help to heal various types of injuries in the body. Growth factors can stimulate the growth of new blood vessels, nerve and connective tissues by the activation of Stem Cells.  And stem cells have a power of regeneration.

Ovarian Rejuvenation Procedure

Ovarian rejuvenation can be done on anytime on women with or without menstruation cycle. The procedure has two steps:

Step 1:

The First step is to isolate the PRP (Platelet-rich plasma), Preparation of PRP begins with the insertion of a needle into the vein in order to get blood in the test tubes. Platelets and White blood cells (WBCs) are separated from the red blood cells (RBCs) and serum by centrifugation process which takes approximately one hour to prepare PRP.

Step 2:

The Second step is Administration of PRP into Ovaries, under an intravenously administered anaesthesia. The isolated PRP (supplied with protein-rich growth factor and stem cell chemoattractants) is injected into the ovaries specifically in the cortical tissue of the patient with the help of transvaginal ultrasound.

Ovarian Rejuvenation has the utmost benefit that it gives a chance to women to become pregnant from her own eggs naturally and also helps in improvement in hormone levels.

After Procedure Precautions

After the procedure, it is very important to keep an eye on AMH (anti-Mullerian hormone), FSH, LH and Estradiol levels along with the ovarian function for 1- 3 months. The values will help to know the positive working of ovarian rejuvenation. Usually, the improvement shows up in 1-3 months but in some cases, it takes more than that. So, the monitoring is done up to 6 months. But the treatment is still in research phase. If ovarian rejuvenation treatment shows a promising future, and then it could help many women who have various types of age-related infertility problems.

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Has the time come for single embryo transfer?

Has the time come for single embryo transfer?

Innovative techniques are persistently growing for infertility treatment. The evolving industry is giving great expectations to most of the people who want to experience parenthood. It seems exciting to be a mother of more than 1 baby and is often a happy moment for every parent. But in multiple pregnancies, there is a risk of complications like premature birth, congenital abnormalities, and mother will more likely to have health issues like gestational diabetes, anaemia, and high blood pressure.  In addition to this, a premature baby needs special care in the Intensive care unit (ICU). So, single embryo transfer (SET) is good option to overcome these problems. Single-embryo transfer (SET) is a process in which one high-quality embryo is placed into the uterus. So, the main focus is to reduce the twin rates in pregnancy by using the single embryo transfer technique.

In the recent years, SET has extensively accepted due to the reason that it reduces the possibility of twins and triplets and also it is safe for both baby and mother. According to the American Society of Reproduction Medicine, single embryo transfer should be considered for patients with favourable prospects usually women who are under the age of 35 or younger with good quality eggs.

Single Embryo transfer (SET) is done when the embryo is at the blastocyst stage. And it is the stage when the best quality embryos can be identified more accurately. A blastocyst stage transfer is a more viable embryo for transfer which reduces the multiple pregnancies. Nowadays, the embryo screening technologies are highly developed, through which embryologist are able to get best single embryo with the goal of achieving a good singleton pregnancy and which reduces the possibilities of multiple gestation and miscarriages.

Through, cryopreservation technology embryos are preserved in frozen condition with no risk even after they have been cultured in the lab to the blastocyst stage. With the help of advanced tools, embryologists can provide the appropriate environment for embryos to grow, as well as methods to recognize that embryo which is likely to develop a baby. This contributes to the probability of success on the first embryo transfer as well as successive transfers.

Due to the advancement of the technology, the majority of patients are able to conceive through single embryo transfer. Success rates of Single embryo transfer (SET) have increased considerably over the past 5 years, making it nearly as likely to achieve a successful pregnancy embryo as with two or more embryos.

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Preparing for Donor Eggs IVF Cycle – Psychological Issues

Preparing for Donor Eggs IVF Cycle – Psychological Issues

In about 50% of our patients, being taken for IVF, the oocyte quality or quantity is the major concern. It’s very easy for us to show you the path of egg donation as it is a routine for us. But we know it is not that simple for you. Though it carries a very high success rate, but psychological implications on the recipient are very high.

The major indications for IVF with donor oocytes in REVIVA are –

  • Premature ovarian failure
  • Menopause
  • Decreased ovarian reserve
  • Endometriosis
  • Recurrent self cycle failures with no proven endometrial or male factor.
  • Genetic causes.

It takes time for the couple to accept the option of Donor eggs, but usually the desire of having a family overcomes this hesitation.

The most important concern of the couple is the quality of genes transmitted to the child. Though the anonymous egg donor is being matched to the recipient as far as possible, the concern always remains in majority of recipient; they are satisfied with their gestational contribution which creates a strong bond.

Another way of dealing with it is to keep the information of type of cycle between the couple only, it will serve you from interrogation eyes and any future problems will be avoided.

On positive note egg donation is associated with many benefit. The most important since eggs are derived from a young woman, they are more likely to produce chromosomally normal embryos and so risk of abortions and birth defects is less.

So, though egg donation is not the first choice of anyone, but it is treatment with very high success rate where it is indicated.

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