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Platelet Rich Plasma
Platelet Rich Plasma
It has been used alongside conventional fertility treatments like In Vitro Fertilization (IVF) to improve egg quality , uterine lining thickness and endometrial receptivity , primarily in the treatment of recurrent implantation failure expired once multiple cycles.
What is PRP?
It is a concentrated blood product that contains high percentage of platelets. In general, whole blood is composed of 4 components:-
- Plasma
- Platelets
- RBC’s
- WBC’s
PRP Process :-
After the collection of blood sample from patient, the sample is being processed in centrifugation machine for certain interval of time
After the completion of time separate the plasma from blood sample and again re- centrifuge for some time
Now the sample is ready to infused in women uterus.
How is PRP used for IVF and other fertility treatments?
PRP is used in a no. of fertility treatments including IUI & IVF to assist with & improve uterine lining thickness/ enhance endometrial receptivity during an embryo transfer.
PRP for Egg Quantity & Quality
It is used to encourage an improvement in egg quality, ovarian rejuvenation & response to stimulate medications.
PRP for uterine lining growth & Endometrial Receptivity
PRP may be used to improve the endometrial receptivity of uterine lining prior to an embryo transfer. This is typically done in 48 hours prior to the anticipated embryo transfer.
During the procedure, approximately 1-3 ml is infused in the uterus using an IUI catheter.
The patient will rests for 30 minutes & is subsequently discharged for a normal daily activity.
If the infusions are intended for lining development (usually for someone with a history of failing to develop an adequate uterine lining).
The first PRP infusion would be done at the initial lining check and then repeated after 72 hrs later and if the lining remains inadequate.
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Things To do To Improve Your Chances of Conceiving Naturally
Things To do To Improve Your Chances of Conceiving Naturally
Natural conception, as easy as it seems, has only a 20% success rate per cycle. So, if you are unable to get pregnant naturally, please do not panic. Good things usually take time.
Having said that, we understand that the process may be worrisome. You may be trying for months without any luck – that can be quite frustrating. But, the good news is that you can do a few things to improve your chances of conceiving naturally. It is all about understanding your body and doing what’s best for it.
Improve your physical health
Physical fitness is of the most importance while trying to conceive. Taking care of yourself and ensuring that you are healthy will automatically increase the chances of conceiving naturally without any intervention. Here are a few helpful tips for you:
- Ensure that you are not overweight or underweight. Both of these conditions affect fertility negatively. If you have chronic weight issues, we suggest that you work with your doctor on the same. Otherwise, you may alter your diet and lifestyle to achieve optimal weight.
- Make exercise a routine and workout at least 3 times a week. The right exercises for you will depend on your body type. But, aerobics, weight training, and yoga have proven to benefit most women.
- Stop smoking and consuming alcohol – this holds true for both partners. Studies over the years have found that even moderate alcohol consumption reduces fertility. Moreover, tobacco reduces the motility of sperm. Even passive smoking can have adverse effects. If you indulge in either or both of these habits, it’s time to stop.
- Try to relax. Stress has severely negative effects on the body and the mind. Excessively stressing about conception may actually be the reason why you are unable to conceive. Try to give yourself a break and take good care of yourself.
Watch your diet
Exercise and diet go hand in hand. Doing just one and ignoring the other is almost as bad as doing nothing. So, along with staying active while trying to conceive, it is important to eat right
Food that must be a part of your diet:
- Water: Drinking water and staying hydrated through the day helps remove toxins from the body. It also helps organ function and stabilizes hormones.
- Whole milk: Whole milk is high-fat dairy that helps successful ovulation and improves fertility. We recommend that you drink 3 glasses of whole milk every day.
- Grains, vegetables, and fruits: All these foods have complex carbohydrates that provide fiber, remove toxins, and improve fertility.
Essential nutrients:
While making diet changes, remember to ensure that you get enough of the following:
- Zinc: Deficiency of zinc causes infertility in men and women.
- Vitamins: Particularly, vitamin B6, C, E, and folic acid enhance the production of male and female hormones.
- Fatty acids: Nuts, seeds, and oily fish can help you get the required fatty acids. They don’t just support fertility but also fetal development.
- Proteins: Consuming protein-rich foods will help enhance the production of sex hormones. We recommend plant-based proteins only. Red meat can be harmful.
Food that you must avoid while trying to conceive naturally:
- Caffeine: Various studies have shown that caffeine causes infertility and can increase the risk of miscarriage as well. So, it is vital that you remove it from your diet entirely.
- Soy products: They cause infertility in men.
- Processed foods: Processed foods must always be avoided but it is even more crucial if you are trying to get pregnant naturally. This is because they are loaded with preservatives, pesticides, and other harmful substances.
- Animal protein: Red meat, etc. increase risk of infertility. Plant proteins are the safest.
Learn about your menstrual cycle
It is not enough to know when your period is due. You must also know when you are ovulating. Keeping track of this is the easiest way to conceive because this is when you are most fertile. There are a few ways to do this:
- Buying ovulation kits: These kits will help you determine whether you are ovulating.
- Following the calendar method: Each cycle lasts for 28 to 32 days. Keeping this in mind, track the first day of your period and determine when the next cycle will start. You may have to track your cycle for a few months to get the exact date but we are assuming you already do that. From the determined date of your next cycle, count backward and note the 8 to 18 days. This is the period when you will ovulate. Ovulation usually occurs only on one day and penetration during that time will increase chances of pregnancy drastically. There are free ovulation calendars available for download as well.
- Checking the cervical mucus: The mucus changes in color and consistency throughout the cycle. Around the time of ovulation, it becomes slippery, stretchy, and whitish – almost like an egg white. Tracking these changes will help you determine when you are ovulating.
- Tracking the basal temperature: All you need is a basal thermometer to check when the basal body temperature goes up. It is usually up immediately after ovulation.
Work on sperm build-up
Both partners have equal roles to play in conception. Tracking ovulation and ensuring you time intercourse in that window is not enough. The male partner must have enough sperm to increase chances of fertilization. Not ejaculating in a while can help with this. So we recommend abstinence for 3-4 days for a positive outcome.
If you have been trying to conceive for over 6 months, it is a good idea to get a few tests done. There might be a medical reason why you are facing problems. Identifying it and solving it could be the breakthrough you are looking for. It will also help you plan the way forward.
Reviva IVF – Your solution to infertility
Reviva IVF offers state-of-the-art IVF treatment centre in Chandigarh. We are a specialty clinic with over 65% success rate. Our team of embryologists, andrologists, and anesthetics will work closely with you to make the journey easy and exciting. We offer the most affordable IVF costs in Chandigarh and surrounding areas to ensure that the procedures don’t take a toll on you. Book an appointment with us now and start the magical journey of pregnancy.
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Fertility Treatment During the COVID-19 Pandemic
Fertility Treatment During the COVID-19 Pandemic
Over the past few weeks, our TV channels, newsfeeds,
social media platforms have been filled with terms such as ‘social distancing’,
‘flatten the curve’ due to the global pandemic i.e. COVID-19. There is no
denying in saying that this pandemic has pressed a pause button to the world.
Whether its planned vacations, weddings, big conferences, sports events or
world championships – everything is on hold.
Now that the world is facing a global health crisis, the cloud of ambiguity and uncertainty is looming larger than ever as many people are questioning how the current restrictions will impact their ability to start or grow their families. Infertility itself is a situation that endures anxiety, feeling of helplessness and fear about the future – and now, there’s COVID-19 pandemic on top of it all.
Current Situation
Given the unknown effects of COVID-19 on fertility
treatment, reproductive medicine societies have recommended the suspension of
new infertility treatment cycles during this time. Couples and especially women
who have invested their time and a lot of money in their treatment may be
frustrated and anxious about the impact of this enforced, yet indefinite delay
on their chances of conceiving. This whole situation has put the health care
providers in the difficult position of trying to balance the patient’s needs
with the current government mandates and expert recommendations.
Infertility Care during COVID-19
There are some guidelines issued by the reproductive
medical associations and authorities to ensure that all patients and staff to
be kept as safe as possible by reducing exposure and therefore complications
that may arise.
With concerning to infertility treatments during the
COVID-19 pandemic, it has been advised to:
- Suspend commencement of new treatment cycles,
including intrauterine insemination,
ovulation induction; and in vitro fertilisation, including frozen embryo
transfers, retrievals, and also suspend non-urgent gamete cryopreservation.
- Cancel all embryo transfers, whether fresh or frozen.
- Continue to provide care and support to patients who
are currently ‘in cycle’ or who require urgent cryopreservation and
stimulation.
- Suspend all the elective surgeries and non – urgent
diagnostic procedures.
How REVIVA is combating the Infertility Treatments
amidst COVID-19?
Its understandable that it can be devastating for those couples who have been trying so hard to build and grow their families to now have to delay treatment due to COVID-19. The goal of this communication is to help patients to have a clearer understanding of the recommendations issued by the government and to help answer questions they may have. Thus, we are providing after-care and support via phone calls whilst keeping your safety on the forefront.
Q: Are elective medical procedures are supposed to stop;
are IVF and other fertility treatments are included in this?
A: Infertility is nothing but a disease, and getting treatment of infertility is medically necessary. IVF treatment is extremely time-sensitive and important but not a medical emergency like treatment of ruptured appendix. We know that many other non-emergency treatments are also being postponed during this crisis scattered globally.
Q: I want to pursue IVF or other fertility treatments.
Should I delay care during the COVID-19 pandemic?
A: To deal with the infertility treatment is in itself is quite daunting, especially when you’re pursuing the dream of starting or growing your family. This COVID-19 crisis has come like an unexpected challenge in the way and the government here and around the world has restricted IVF fertility centre in performing treatments.
As fertility care requires a lot of interaction and
communication with many people and person-to-person meet which might increase
the likelihood of getting infected in one way or the other. so, this is why we
have postponed infertility care until the crisis passes.
Q: Are my frozen embryos, eggs, or sperm safe?
A: Yes. As there is no immediate threat to the safety
of cryopreserved eggs, embryos, or sperm. We have some policies and advanced
procedures which maintain the life of embryos, eggs and sperm.
Q: How safe is the clinic and what cleaning protocols
it is following?
A: Our clinic is following all the cleaning and safety
protocols mandatory as per the government regulations. We have been keeping a
close check on every nook and corner and our cleaning staff is taking care
diligently. And, we would be following these measures even after this crisis
gets over for the safety of our patients and staff members.
Q: Can I still have a medical, counselling or nurse
consent consultation?
Right now, we are encouraged to minimize in-person
interactions and instead utilising Telehealth conversations via phone or video
chat. Patients who are undergoing through a fertility cycle and need
after-care, we are here for you providing support and all the possible options.
Therefore, COVID-19 has cast the future of IVF and the
fertility sector into uncertainty.
To be noted, if you have been exposed to COVID-19 or
may be at risk, we recommend you to postpone the treatment until cleared by
your primary health care provider. This is all in the interest of your safety
and the safety of our staff members and other patients. For more information,
you can email us or call us. We all are in this together.
As we are facing this unprecedented health crisis due
to the wide-spread of the coronavirus, we recognise and appreciate the efforts
and response of the entire army of doctors, staffs, and nurses who are
tirelessly doing their jobs and helping the patients from this dreadful
disease.
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Getting pregnant after 40 and the treatment options – Reviva IVF
Getting pregnant after 40 and the treatment options – Reviva IVF
The reproductive potential of a woman declines after 40. So, chances of natural conception reduce with age. Delaying in pregnancy can be due medical reasons or lifestyle which can be a leading cause of ovarian aging. Women are born with millions of eggs but with age, the quality & number of eggs become less. But if natural conception is not happening due to age factor then a patient must go for a fertility checkup.
How pregnancy can be achieved in 40’s?
Achieving pregnancy after 40’s needs a healthy lifestyle. Taking good care of health, eating a healthy diet, and regular exercise can improve the chance of your pregnancy. Since the age is the major factor so if a woman has aged more than 40 yrs & trying for a baby without any success then the patient should seek the advice of a fertility doctor. The infertility factor can either be associated with male or female. So it is important to know the cause. In women, the problem can be blocked fallopian tubes, endometriosis, infections, fibroids etc. In males, the problems can be with semen sample like, Azoospermia, oligospermia, Globozoospermia etc. IVF treatment for such patients is the only answer to achieve a successful pregnancy.
If a couple is undergoing IVF treatment patient must undergo necessary investigations to make a correct diagnosis. In women, blood investigation is performed to check the hormonal levels – Estrogen, progesterone, LH levels, AMH level (check ovarian reserve), followed by Ultrasound to monitor any fibroid or lesions etc. Whereas, in male blood tests for viral markers, semen analysis & culture is done.
Treatment available after 40
Assisted Reproductive Technology (ART) process which is commonly known as Invitro Fertilization (IVF) is the treatment available for such patients. Through IVF treatment, it is to ensure that a patient is able to get children after taking proper treatment. In the process, the embryo is made outside the human body in in-vitro conditions and on Day 3 or Day 5 it is transferred to the uterus for further development. The whole treatment can be done in 2 weeks.
Name of some treatment Available:
- IUI (Intrauterine Insemination)
- IVF (Invitro-Fertilization)
- ICSI (Intracytoplasmic Sperm Injection)
- LAH (Laser Assisted Hatching)
Reviva Fertility clinic & IVF Centre in Chandigarh offers you all kind of latest fertility techniques to treat infertility problem.
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Importance of Quality Control in IVF Lab
Importance of Quality Control in IVF Lab
Quality control (QC) is the most important component of the IVF Clinic. QC evaluates the quality of the procedure & its outcome. It is mandatory to monitor laboratory conditions (Air Quality, Temperature, and VOC’s etc), Stimulation protocols, Culture media & technical skill coordination etc to ensure quality control. The IVF lab which follows good laboratory practices they can facilitate the results of IVF by giving the best outcome to their patients.
Need of Quality Control in IVF Lab
- It ensures the quality of the procedure
- Increase the success rate
- Increase the reliability of IVF lab
- Complete traceability & Documentation
- Build up IVF team confidence
- IVF Laboratory Equipments
Incubators The change in temperature & Co2 level can affect the oocytes & embryos quality. So, carbon dioxide & temperature should be recorded on daily basis. If anything altered it should be calibrated as per requirement.
Laminar Air Flow: The laminar flow need to clean on daily basis before & after the completion of task.
Refrigerators: The location of the refrigerator should be outside the core embryology area as it releases harmful gases which are not good for IVF Lab. Also thermometer should be placed inside the refrigerator to see the temp on daily basis.
Microscopes: They should be cleaned everyday to remove unwanted dust particles.
Heated Stages: Temperature is a very crucial parameter as it can cause spindle damages etc. So, gametes handling should be done strictly on heated stages at 37°c to avoid any kind of damage.
Below given table will help to know that how often the test is done to check equipment working.
| Equipment | Test | Duration |
| Incubator | CO2 ,Temp | Weekly |
| Laminar Air Flow | Environment | Monthly |
| Refrigerators | Temp | Weekly |
| Microscope | Function | Monthly |
| Heated Stages | Temp | Monthly |
- Culture Media
Oocytes & embryo are very sensitive & a little change in their environment like ph, osmolarity etc can cause harmful effects to them. So the cultural conditions should be favorable for them. So it is important to understand the need of culture media
- While receiving media from any company ensure that the cold chain of media is well maintained. Never accept broken seal of the order.
- Always see the expiration date of Culture media before use in any case.
- Always store your media in refrigerator with required temperature conditions.
- IVF Laboratory Environment:
The laboratory environment is mostly affected by the following reasons:
- If clinic is located near to construction sites, on highway, factories then there are a major risk of dust particles & pollutants. So, Hepa Filter is necessary for such laboratory. As it removes 99.99% of small 0.3 microns in size dust particles.
- Use of cosmetics in IVF should be prohibited. Cosmetics emit VOC’s & can cause negative effect to embryos.
- Laboratory cleaning is done on daily basis using disinfectants.
- If any kind of fluid spilage is found then it should be cleaned with 5.25% sodium hypochlorite.
- Protocols to be followed when working IVF Laboratory:
- IVF Laboratory should have well trained staff. The embryology work is very sensitive so expertise is required.
- The laboratory should keep on updating the protocols. Inhouse modifications in methodology should be done for betterment.
- IVF Lab should remain up to date with the latest technology.
- Dishes Preparation should be done at room temperature. One culture dish is prepared at a time to maintain the osmolarity.
- Ethical practice while handling the gametes. Label the dishes before OPU. Avoid mixing of samples by labeling containers.
- Witnessing should be a compulsory practice in IVF laboratory.
- Wearing gloves, cap & mask in laboratory is must. Hand washing is essential before entering IVF laboratory.
- Discard sharp objectives & pipettes after single use.
- The documentation is very important in IVF lab system. It helps to recall the past events. So proper documentation in IVF is necessity. For eg: Patient Records, QC data, Complaint Data
QC is the essential component of IVF laboratory. It is our responsibility not a burden. Infact, it helps in troubleshoot. QC ensures the success rate & even the reputation of the clinic. And we at Reviva Fertility Clinic & IVF Centre In Chandigarh follow all the ethical practices & make sure at every step that the outcome should not be affected at any cost. For more information on the IVF Procedure and their cost in Chandigarh you can contact us: 8288028667
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Culture Media
Culture Media
Assisted Reproductive Technology results have been improved due to the improvement in culture media conditions. There are number of commercially available culture media in the market with components like protein, antioxidants, carbohydrates etc. In this blog, we are going to discuss the key components of media & how they support to embryo growth.
What is Culture Media?
Culture media is the artificial environment given to the embryos for growth & development. Culture media is based on two philosophies:
- Back to nature Principle
- Let embryo decide the principle
In nature principle, the media components try to imitate the components of a female reproductive system .Which means the media is formulated sequentially according to the embryo developmental need i.e. from zygote to a blastocyst. Whereas, Embryo chooses principle is single step or monoculture formulation in which the media is supplemented with all the macromolecules and then embryo utilize the macromolecules according to its requirements.
Key Components of Embryo Culture Media
Water
Most of the culture media are made up of 99% of water. As, the goodness of media depends upon the quality of water. So, the water sources should be good.
Ions
The role of ions in the media is to maintain the osmolarity. The ions present in culture media is Na, Cl, P, Ca, Mg, S, K, etc. Osmolarity of medium affects cell volume & embryo development. Elevated osmolarity can result into developmental arrest. Osmolalities of culture media should be in the range of 260 to 298 milliosmoles.
Carbohydrates
Carbohydrates are the key source of energy for embryo growth. The media consist of pyruvate, lactate and glucose. In the initial stage of development pre compacted embryo utilizes the pyruvate as primary source of energy .However, in post compaction stage the embryos use glucose for expansion.
Amino Acid
These are important regulators serve as energy sources. Essential & non essential amino acid stimulates the production of ICM of blastocyst. Whereas trophoectoderm formation & hatching in blastocyst is initiated by non-essential amino acids (Glutamine).
Antioxidants
Invitro embryos when exposed to culture conditions they may experience oxidative stress due to production of Reactive Oxygen Species (ROS) Which have a negative impact on the development of embryo. Media should be supplemented with antioxidants such as Lipoate to avoid stress on embryo produced by ROS.
Antibiotics
To avoid bacterial contamination in culture media antibiotics like gentamycin, streptomycin are added to media.
Proteins
Protein is the common macromolecule in human embryo culture media such as Human Serum Albumin (HSA). It aids in embryo development. They also maintain membrane permeability & osmoregulation while manipulation of gamete in vitro.
Buffer System
The suggested pH range for culture media is 7.2 -7.4. Most of the culture media have bicarbonate buffer system to sustain the pH in the tolerable range. For handling gametes outside the incubator HEPES & MOPS are preferred.
Growth Factors & Hormones
Embryos are exposed to a blend of maternal hormones & the role of hormones in embryo development is uncertain. Growth factors have considerably role in growth & differentiation of Day4 Morula to a Day 5 Blastocyst. Even due to the addition of growth factors to the media have drastically improved the implantation rates.
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IVF treatments in India boasts lower cost, yet higher success rates
IVF treatments in India boasts lower cost, yet higher success rates
IVF or In vitro fertilization treatments are popular all over the world. However, the attention of IVF treatment seekers has turned to India as their choice of the treatment location. Many people from the western world are visiting India for this purpose.
Affordability of the cost of IVF treatment in India coupled with excellent success rates attract many couples from all over the world, and their confidence to choose India as their IVF treatment destination has increased over time. The average cost of the IVF treatment in India is usually between Rs. 250,000 – 450,000 for a basic IVF treatment cycle. However, advanced IVF treatment as if ICSI (Intracytoplasmic sperm injection) or ET (Embryo transfer) costs 120,000 – 150,000 in addition to the IVF basic treatment cycle cost. This is only a fraction of a treatment cost when compared with the IVF treatment costs in the western world.
In addition, the cost of IVF treatment hugely varies between various cities of India. The cost of IVF treatment in Delhi is totally different from treatment cost in Mumbai or in Chennai. Due to this reason, many couples who live in different parts of India travel to other locations to undergo these IVF treatments at an affordable cost. Here is how the infertility treatment cost in India varies according to the location; Mumbai 200,000 – 300,000, Bangalore 160,000 – 175,000, Chennai 145,000 – 160,000, Delhi 90,000 – 125,000, Nagpur 75,000 – 90,000, Hyderabad 70,000 – 90,000, Pune 65,000 – 85,000 and etc. The treatment cost in Chandigarh is considerably low when compared with some of the locations above, and at Reviva clinic you could receive world-class medical care for the same cost.
Every couple should keep in mind to analyze the package that comes with the IVF treatment beforehand in order to avoid any hidden charges. For instance, Reviva Infertility and IVF Clinic offer special IVF package that includes all examinations costs as if for ultrasound examination, the cost for all types of blood tests that required during IVF treatment, anesthesia cost, advanced IVF treatment cycle options as if ICSI and ET. Besides, Reviva clinics package also incorporates laboratory charges and even it includes the cost of day care hospitalization that is required during IVF treatment cycle and guarantee of no hidden fees. All charges are included and elaborated in the treatment packages so that preparing for the treatments financially would not bring any surprises throughout the process.
As India is one of the countries to receive infertility treatments for a lower cost, you should consider visiting Reviva Clinic at Chandigarh to make your dream come true. Along with the lower cost of treatments, the lower costs of accommodation and also travelling will reduce additional costs you will have to bear during the visits. That is why many people consider India today as to be a leading country for medical tourism. If you are planning for IVF treatments and wondering where to seek the best care, then you are in the right place. Reviva clinic is more than happy to hear from you.
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Oocyte Grading
Oocyte Grading
An oocyte is a female gamete which is involved in reproduction. It is one of the largest cells in the body 120 microns in diameter and develops in the ovarian follicle during oogenesis. On the basis of oocyte grading we can find the ideal oocyte for fertilization. While Oocyte Pickup, on the basis of cumulus we can get an idea of oocyte maturity.
- Immature – The immature oocytes are Germinal Vesicle and they have tightly packed corona cells with little cumulus.
- Intermediate– The nuclear maturity of these oocytes is Metaphase I. The corona and cumulus cells are tightly packed.
- Mature- These oocyte are at Metaphase II stage and they appear like sunburst of corona cells with expanded and abundant cumulus.
- Postmature– These types of oocytes are mature ones which have dark Cumulus oocyte complex. In which corona cells begin to degenerate.
On denudation of cumulus–corona cells, we can better appreciate the maturity and morphology of oocyte before fertilization. Below given picture can give you an idea about the oocytes maturity.
Germinal vesicle has a visible intracytoplasmic nucleus. Metaphase I oocyte neither has Germinal Vesicle nor polar body. Metaphase II stage when it has a visible polar body.
We can grade the oocytes by looking at its Zona Pellucida, perivitelline space (PVS ) shape, polar body (PB) morphology , Ooplasm characteristics.
1.Zona Pellucida: The Zona Pellucida is the outer layer of oocyte .The normal thickness of ZP is 17-18 microns. If the thickness of Zona is greater than normal then after ICSI Laser Assisted hatching (LAH) is required. If thickness is very low then there is a chance of early hatching or damage can cause to oocyte while doing denudation. The alterations in Zona Pellucida appearance could be caused by secretion problems of the glycoprotein matrix.
| Zona Pellucida Assessment | Explanation |
| Normal | Thickness of 17-18 microns with even surface |
| Thin | If the Zona pellucida is less than normal |
| Thick | If Zona pellucida is more than 25 microns |
| Abnormal | If the shape of Zona pellucida is irregular |
- Perivitelline Space: This is the space between Zona and oolemma membrane known as PV space. We can see a polar body in this space. Sometimes it is large in size or may be absent.
| Perivitelline Space Assessment | Explanation |
Normal | The Ooplasm is slightly away from the ZP in the surrounding area of the polar body |
| Large | the Ooplasm is away from the ZP leaving a large space around the cytoplasm |
| Fragmented | Fragments and debris |
b) Polar Body: The polar body should single and round in shape and in total 5% of the cell volume.
| Polar body Assessment | Explanation |
| Normal | Ovoid & round in shape, with 5% of cell volume. |
| Fragmented | Polar body is irregular and dissociating into small fragments |
| Giant | Large in size |
c) Ooplasm: The Ooplasm is the cytoplasm of egg. Sometimes it has some inclusions and clusters which can be graded to get the best oocyte.
| Cytoplasmic Inclusions | Explanation |
| Vacuoles | These are fluid filled bodies. Appears as a vesicle in the cytoplasm. They can be single or abundant. |
| Refractile Bodies | Appears like dark dots of diverse sizes (lipofucsin) |
| Smooth Endoplasmic reticulum | Appears as a flat elliptical disk |
| Granulation | Uneven patches of granules in the Ooplasm |
From such assessment we can only find the ideal oocyte for fertilization. But these parameters are still controversial for embryo development and implantation. Like abnormal Zona Pellucida, Perivitelline space fragments, size and morphology are still controversial. But the presence of inclusions bodies like vacuoles, Refractile bodies , SER in large number can be detrimental.
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Reviva clinic – one of the best in IVF treatments
Reviva clinic – one of the best in IVF treatments
Infertility has become a more frequent problem today. The modern lifestyle and environmental factors have been able to affect the fertility of many men and women in a significant way. If you are one of those living in the anguish and thinking about an IVF treatment, India could be the best place to visit for your treatments.
India is one of the leading destinations for advanced IVF treatments in the world today. Therefore, it is no surprise that many infertile patients from around the world come to India gathering their hope to succeed. While there are many IVF centers in different parts of the country, the best IVF center in India, namely Reviva clinic is located in Chandigarh. As Reviva clinic boasts about its highest success rate, the number of patients visiting for treatments has significantly increased each year and is still on the rise.
India is one of the most medically advanced countries in Asia and possesses all know-how strategies and modern technology to treat men and women who look forward to having a child. Reviva clinic being the best IVF center in Chandigarh possesses the modern technology and access to advanced interventions, which were once available only in the leading countries of the Western world. Today, you can visit Reviva clinic and experience the state-of-the-art medical care and be sure of a higher success rate. While you get treated at the best IVF center in India for your treatments, you can also enjoy the calming nature, warm hospitality and a rich culture that will even increase your hopefulness towards success.
Nothing is more comforting than being surrounded by a team of medical specialists who understands and work towards your success. This is what the Reviva Clinic – the best IVF center in Chandigarh has expertise in. A group of specialized medical professionals works together in the IVF centre, and they prioritize the individual needs of every patient in order to achieve success.
One of the best reasons to get IVF treatments in India is the lower cost. Yes, although Reviva clinic is the best IVF center in India, the cost is almost as half as of that is in the advanced countries of the world. State of the art, advanced strategies, and modern interventions would not be accessible at a lower cost in any other part of the world as you would in India. This has allowed many couples to save money for their childbirth rather than spending it all on the IVF treatments.
Reviva clinic is not only specialized in IVF treatments but also carry out other advanced fertility treatments such as ovulation induction, follicular monitoring, IUI, surgical sperm retrieval, oocyte donation, etc. You could find many solutions under a single roof, and that is why we say that Reviva clinic is the best IVF center in Chandigarh.
If you are looking forward to making your dream come true and to get the world’s best medical care, then you are in the right place. Come and get treated in the best IVF center in India!
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