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Decoding The Signs of Bad Egg Quality – A deep Dive into Fertility



Intracytoplasmic Sperm Injecton (ICSI) 

Although Intracytoplasmic sperm injection (ICSI)  was introduced as an add on procedure to In vitro fertilization (IVF)  for couples with severe male factors , now a days it is routinely used in most of the IVF centers.  ICSI  involves injection of single sperm into a mature egg.

Intracytoplasmic Sperm Injecton (ICSI)

ICSI has a clear cut edge in male factor infertility like low sperm count , poor sperm motility , abnormal sperm morphology , nil sperm count due to blockage etc. ICSI is also the best option when fertilization rates in previous cycles have been low.

 In these cases the risk of fertilization failure after conventional IVF are high as the poor quality sperm may fail to penetrate the egg and result in failure. However, ICSI is Labour intensive and more expensive than Conventional IVF.


Conventional IVF  involves standard  insemination of eggs collected by egg retrieval and husband semen sample .

IVF is more successful in young couples with good ovarian reserve and normal semen parameters .Your chances of having a healthy baby using IVF depend on many factors, such as your age and the cause of infertility.

The current available studies that compare ICSI and IVF in couples with no male factor problems show neither method was superior to the other in achieving live birth, complications like multiple pregnancies etc.

The choice between both the fertility treatments would mostly rely on diagnosis and recommendation of your fertility specialist while its always great to have basic understanding of the process benefit & difference.

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Fertility in couples – things you need to know

Fertility in couples – things you need to know

Infertility is quite a scary term for couples who are eager to become parents. The fear increases with each passing day because 86% of couples successfully conceive within the first few months. Less than 10% conceive within a year.

However, there is a lot of uncertainty and misunderstanding around the word “infertility” and this creates more panic than necessary. In this blog article, we will speak in depth about it along with treatment options so that you walk the path of parenthood without any qualms.

What is infertility?

Infertility is the inability to conceive a child. A couple may be deemed as infertile after over a year of unprotected sex and no success. The usual thumb rule is that failure to conceive even after 15 months or so is an infertility case.
Infertility can be due to various reasons, sometimes unknown. Most of these reasons can be identified and treated to successfully foster pregnancy.

Infertility problems in couples

Infertility can be caused due to health problems in the female partner, male partner, or both. Even though consultations start with women heading to the fertility clinic, complications may be in the male partner as well. This is why it is recommended that both partners get the necessary tests done. Common reasons behind infertility problems are:

  1. Endometriosis
  2. Ovulation disorders
  3. Problems in the fallopian tube (Damage)
  4. Advanced age
  5. Uterine fibroids
  6. Unexplained infertility (14% of total infertility cases are unexplained)
  7. Hypothalamic disorders, gonad disorders, and sperm issues in men

The need for infertility treatment

Gone are the days when infertility was the end of the world. Today, your dream of being a parent can come true despite complications and hindrances because there are multiple treatments that you can try.

Based on the situation, your fertility clinic will provide the best solution. We have enlisted the most popular solutions here:

In-vitro fertilization or IVF

IVF is an intricate procedure in which the clinic will fertilize the egg in the laboratory. The sperm and egg will be taken and fused under stipulated conditions to aid fertilization.

IVF is currently the most successful method of fertilization and is used worldwide for this exact reason. No matter what the cause of infertility maybe, IVF is often the solution.

Stimulating ovulation

If infertility is caused due to ovulation disorders, stimulating ovulation through medication and injections maybe tried. The idea is to assist the female partner in ovulating and releasing mature eggs.

Intracytoplasmic Sperm Injection (ICSI)

ICSI is a common treatment for male reproductive dysfunction in which the sperm is injected directly into the mature egg.

Intrauterine Insemination (IUI)

IUI, also known as Artificial Insemination, is a widely popular method used in cases where there is concern regarding fertility or damaged fallopian tubes.

There are multiple other treatments as well such as the use of donors and surrogacy, which are considered based on the severity of the situation and the comfort level of the couple.

Is it the right time to change your fertility clinic?

While infertility treatments may take time, there may come an instance when you might question whether you chose the right fertility clinic. If you see any of the following red flags, it could be time to change your fertility clinic:

The physician does not have a clear conversation

Good physicians do not demand that you listen quietly to them and do as told. They are always open to discussions and answering questions about the procedure.

They often tell you why the procedure is right for you and discuss alternatives as well. If your physician does not encourage this, you should look for a better clinic.

Unprofessional behavior

The most common unprofessional trait we see is making patients wait despite appointments. Appointments are commitments that the physician must honor as well.

If he/she makes you wait all the time and every appointment takes much longer than anticipated, it is a sure red flag.

Not discussing budget or expenses

Infertility treatment is a psychologically and financially heavy process. Couples look for clinics that can empathize with them and speak to them about all the options keeping budget in mind.

Couples may need to take multiple steps including loans before starting the process. Shutting them out and not listening to them shows that the clinic is less than supportive.

Not respecting privacy

Clinics that do not understand the need for privacy and physicians who would meet with multiple patients at once are best avoided.

Always trust your gut instinct and exit at the first negative sign. Infertility treatment is a challenging process that needs timely attention.

Sticking to the wrong clinic may knock precious time off, which is very crucial.

Choosing the best IVF Clinic in Chandigarh

The best IVF clinic in Chandigarh will not just provide the right options for treatment, but also discuss closely with you, empathize and come up with the right solution.

At Reviva IVF, we understand the challenges and difficulties you are going through, and do our best to ease your pain – physically and emotionally. All our physicians and team members work closely keeping budget constraints in mind so that the journey to parenting is fruitful and not taxing.

At Reviva IVF, we understand the challenges and difficulties you are going through, and do our best to ease your pain – physically and emotionally. All our physicians and team members work closely keeping budget constraints in mind so that the journey to parenting is fruitful and not taxing.

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Things To do To Improve Your Chances of Conceiving Naturally

Things To do To Improve Your Chances of Conceiving Naturally

Natural conception, as easy as it seems, has only a 20% success rate per cycle. So, if you are unable to get pregnant naturally, please do not panic. Good things usually take time.

Having said that, we understand that the process may be worrisome. You may be trying for months without any luck – that can be quite frustrating. But, the good news is that you can do a few things to improve your chances of conceiving naturally. It is all about understanding your body and doing what’s best for it.

Improve Your Physical Health

Physical fitness is of the most importance while trying to conceive. Taking care of yourself and ensuring that you are healthy will automatically increase the chances of conceiving naturally without any intervention. Here are a few helpful tips for you:

  • Ensure that you are not overweight or underweight. Both of these conditions affect fertility negatively. If you have chronic weight issues, we suggest that you work with your doctor on the same. Otherwise, you may alter your diet and lifestyle to achieve optimal weight.
  • Make exercise a routine and workout at least 3 times a week. The right exercises for you will depend on your body type. But, aerobics, weight training, and yoga have proven to benefit most women.
  • Stop smoking and consuming alcohol – this holds true for both partners. Studies over the years have found that even moderate alcohol consumption reduces fertility. Moreover, tobacco reduces the motility of sperm. Even passive smoking can have adverse effects. If you indulge in either or both of these habits, it’s time to stop.
  • Try to relax. Stress has severely negative effects on the body and the mind. Excessively stressing about conception may actually be the reason why you are unable to conceive. Try to give yourself a break and take good care of yourself.

Watch Your Diet

Exercise and diet go hand in hand. Doing just one and ignoring the other is almost as bad as doing nothing. So, along with staying active while trying to conceive, it is important to eat right

Food That Must Be a Part of Your Diet:

  • Water: Drinking water and staying hydrated through the day helps remove toxins from the body. It also helps organ function and stabilizes hormones.
  • Whole milk: Whole milk is high-fat dairy that helps successful ovulation and improves fertility. We recommend that you drink 3 glasses of whole milk every day.
  • Grains, vegetables, and fruits: All these foods have complex carbohydrates that provide fiber, remove toxins, and improve fertility.
Essential Nutrients:

While making diet changes, remember to ensure that you get enough of the following:

  • Zinc: Deficiency of zinc causes infertility in men and women.
  • Vitamins: Particularly, vitamin B6, C, E, and folic acid enhance the production of male and female hormones.
  • Fatty acids: Nuts, seeds, and oily fish can help you get the required fatty acids. They don’t just support fertility but also fetal development.
  • Proteins: Consuming protein-rich foods will help enhance the production of sex hormones. We recommend plant-based proteins only. Red meat can be harmful.
Food That You Must Avoid While Trying to Conceive Naturally:
  • Caffeine: Various studies have shown that caffeine causes infertility and can increase the risk of miscarriage as well. So, it is vital that you remove it from your diet entirely.
  • Soy products: They cause infertility in men.
  • Processed foods: Processed foods must always be avoided but it is even more crucial if you are trying to get pregnant naturally. This is because they are loaded with preservatives, pesticides, and other harmful substances.
  • Animal protein: Red meat, etc. increase risk of infertility. Plant proteins are the safest.
Learn About Your Menstrual Cycle

It is not enough to know when your period is due. You must also know when you are ovulating. Keeping track of this is the easiest way to conceive because this is when you are most fertile. There are a few ways to do this:

  • Buying ovulation kits: These kits will help you determine whether you are ovulating.
  • Following the calendar method: Each cycle lasts for 28 to 32 days. Keeping this in mind, track the first day of your period and determine when the next cycle will start. You may have to track your cycle for a few months to get the exact date but we are assuming you already do that. From the determined date of your next cycle, count backward and note the 8 to 18 days. This is the period when you will ovulate. Ovulation usually occurs only on one day and penetration during that time will increase chances of pregnancy drastically. There are free ovulation calendars available for download as well.
  • Checking the cervical mucus: The mucus changes in color and consistency throughout the cycle. Around the time of ovulation, it becomes slippery, stretchy, and whitish – almost like an egg white. Tracking these changes will help you determine when you are ovulating.
  • Tracking the basal temperature: All you need is a basal thermometer to check when the basal body temperature goes up. It is usually up immediately after ovulation.
Work On Sperm Build-Up

Both partners have equal roles to play in conception. Tracking ovulation and ensuring you time intercourse in that window is not enough. The male partner must have enough sperm to increase chances of fertilization. Not ejaculating in a while can help with this. So we recommend abstinence for 3-4 days for a positive outcome.

If you have been trying to conceive for over 6 months, it is a good idea to get a few tests done. There might be a medical reason why you are facing problems. Identifying it and solving it could be the breakthrough you are looking for. It will also help you plan the way forward.

Reviva IVF – Your Solution to Infertility

Reviva IVF offers state-of-the-art IVF treatment centre in Chandigarh. We are a specialty clinic with over 65% success rate. Our team of embryologists, andrologists, and anesthetics will work closely with you to make the journey easy and exciting. We offer the most affordable IVF costs in Chandigarh and surrounding areas to ensure that the procedures don’t take a toll on you. Book an appointment with us now and start the magical journey of pregnancy.

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Things you must know before starting IVF

Things you must know before starting IVF

We would like to commend you and your partner on your decision to undergo IVF. You are extremely brave.

The road ahead can be daunting when you don’t know what to expect and how to prepare yourself for the journey. IVF takes time and getting ready for it is important – and we don’t just mean financially. We mean that you must be prepared emotionally and physically as well. To help you with this, we have jotted down the most important things you must know before starting IVF.

IVF requires patience and optimism

The procedure involves multiple steps and cycles that can stretch for weeks. Different couples respond differently to the treatment and that is why it can be stressful to go through it. There’s no formula about body response and the time it will take for the procedure to show results. This is why, we urge you to have a patient and optimistic mindset right from the get-go.

Around 50% of couples see results in the first cycle but the rest require at least one additional cycle. Each cycle takes about 4 weeks. If the first cycle does not show results, it is very crucial not to be disappointed and worried. Brace yourself for the journey along with your partner – there will be light at the end of the tunnel.

The cost is an important consideration

Cost is a huge factor because the procedure can be expensive. However, the approach here must be different. There are many important things to consider to understand whether you will get value for money. A few of these are as follows:

  • The success rate of the clinic: Good clinics usually have an excellent success rate, making them more suitable. The chances of having to go through fewer cycles are also high if the success rate is good. This means that even if the cost is slightly on the higher end, you will save money on the whole and there will be less hassle as well.
  • Transparency: Hidden costs are a major concern in most cases. What’s discussed upfront may not appear in the final invoice due to a large number of charges that the clinic initially does not speak about. Speaking to the doctors will give you a fair idea about this. Notice how open they are about the procedure, whether they are giving out details of the cycles, etc. and you will be able to tell if they are transparent. Reviews come in handy here as well. So, be sure to explore them.
  • Whether it is a specialty clinic: A super-specialty clinic accommodates multiple disciplines of medicine and may not be the right choice especially during a pandemic. A specialty clinic, on the other hand, is much safer. Also, since the entire clinic is dedicated to IVF and infertility, there will be better equipment, expert doctors, focus, and better success rate.
  • How long the clinic has been in business: This factor will help you understand how well the clinic has fared and whether it is thriving in the space. If the clinic is new, you may not have previous results to go by.
  • Payment options: Does the clinic offer 0% EMI? If yes, check if the cycle rates are higher than its competitors. Does it have tie-ups with banks for loans? This may help you get a loan without extra trouble.

When you evaluate the IVF cost, it is crucial that you tap into each of these points. It will give you a 360-degree understanding of the clinic, making the choosing process quite easy.

Your body needs to prepare

Physical preparation is a must for the IVF procedure and the 9-month journey after conception. Your body must be ready for it. In other words, it should be fit and healthy. If you lead a rather unhealthy lifestyle such as low physical activity, smoking, obesity, etc., you have to start working on it. The great news is that a few simple changes can have a huge impact on sperm count and your fertility. So, based on your partner’s and your physical fitness, you can start taking the necessary steps. A few doctors may also recommend a specific IVF diet. You will need to follow this for at least 2 months before you can start the IVF procedure.

Stress is harmful

Anxiety and confusion are a part of the IVF journey especially in the beginning but these factors lead to stress. Stress makes conception harder than it needs to be. This is because it directly affects the body! Multiple studies have, in fact, proven that women who did not stress much during the process were more likely to see positive results.

We realize that it is easier said than done. Stress is an obvious part of a life-altering process especially when you don’t know what to expect. This is why, the best way to avoid stress is to learn about the process, what to expect, and what needs to be done. We recommend that you choose a good IVF clinic and speak to the doctors regularly. Have all your questions answered so that you know exactly what to expect. This will ward off the fear of the unknown quite significantly.

Be prepared for some discomfort

We have seen many couples fret about pain and discomfort due to the medication. The injections themselves are standard and do not cause much pain. But, they have been known to show side-effects such as breast tenderness, mood swings, and abdominal pain. Headaches, nausea, and bloating may also be experienced. Having said that, you must note that “severe” pain is not very common. It only happens to a few women. Progesterone shots may also cause bruising and pain.

It can be incredibly difficult to take so much pain but we urge you to look at the bigger picture – 9 months down the line, you will realize that the pain was indeed worth it.

You may need a support system

The burden of infertility is indeed too much to take. Adding to this, the taboo surrounding it, the fear of society, and the worry to keep it under the covers can be too much to handle. You and your partner must emotionally be there for each other, of course, but along with that you will need a support system of your closest family members and friends. They will provide a comforting shoulder through the process.

Don’t hesitate to reach out to the ones you trust the most – they are there for you.

It may not feel like it at the moment, but something wonderful will come out of this journey. Choosing a good IVF clinic and working closely with your doctor will alleviate most of the stress revolving around it. We hope the aforementioned points work as a positive light as you begin what we hope will be a magical phase in your life.

Choosing the right IVF clinic in Chandigarh

If you are on the lookout for a specialty IVF centre in Chandigarh, we invite you to check Reviva Infertility and IVF Centre Chandigarh. We provide state-of-the-art medical services to help and support you through the treatment. Our success rate is around 50-60% and we offer the most competitive IVF costs in Chandigarh. Contact us to know more and book an appointment.

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Embryo Implantation, Process & their stages – Reviva IVF

Embryo Implantation, Process & their stages – Reviva IVF

embryo implantation process and steps

What happens in your uterine cavity after the implantation of an embryo? Let’s have detailed information about implantation through this blog.

What is Implantation?

It is the process in which the fertilized egg or a blastocyst gets attached to the endometrial wall of the uterus to attain pregnancy. During this stage, the embryo establishes a strong connection with the maternal circulation and starts its embryonic developmental journey.

The endometrium is receptive to a fertilized egg for a shorter period in the luteal phase which is termed as “Implantation window”. The window lasts for 4 days & follows up to 6 days after the peak of LH levels. And it is essential for the blastocyst to reach endometrium during the implantation window in order to get a successful implantation. Any delay in the blastocyst transport can cause loss of endometrial receptivity. Blastocyst Implantation occurs 6-8 days after fertilization.

Embryo Implantation process is mainly divided into three stages:

  1. Apposition 
  2. Adhesion 
  3. Invasion

1. Apposition:

In this stage, the blastocyst sheds its zona and approaches the endometrium with a particular orientation. The finger-like projections known as chorionic villi helps to bring the blastocyst nearer to the uterine epithelium. The uterine epithelium cells have glycoprotein on its surface which acts as a barrier between blastocyst and endometrium. The blastocyst uses its enzymes to digest the glycoprotein which results in interlinking of trophoectoderm with luminal epithelial cells.

2. Adhesion:

Attachment occurs on 6th or 7th day post ovulation. At this stage, the strong association is established between endometrium and blastocyst. Due to enzymatic breakage of glycoprotein, the adhesion molecules (includes cadherins, intergrins, glycan, & lectin etc.) in blastocyst and endometrium have free accesses to each other.

3. Invasion:

In this stage, the embryo needs to connect with the mother for development. The blastocyst completely penetrates the endometrium by day 9. The blastocyst consists of two main components – The trophoblast & the Inner Cell Mass (ICM). The function of trophoblast cells in the embryo is to invade the endometrium to build maternal connection with an embryo. The Inner cell mass give rise to a fetus. As embryonic trophoblast makes contact with endometrium it further differentiates into two layers: Cytotrophoblast & Syncytiotrophoblast. 

The ICM in the embryo makes a two differentiated layers hypoblast & Epiblast. The cavity arises between Epiblast & Cytotrophoblast is known as amniotic cavity. Cells originate from hypoblast which forms a thin membrane called as exocoelomic membrane. Cells of hypoblast and exocoelomic membrane forms wall of primary yolk sac. The growth of trophoblast forms Cytotrophoblast & Syncytiotrophoblast becomes quiker at this stage. The lacunar networks begin to form in the Syncytiotrophoblast & by the 12th  day the lacunar networks stops growing .The uterine blood vessels in the endometrium comes in contact with lacunar networks which directs the placental trophoblast to maternal blood circulation. Also the endometrial stroma becomes dense cellular matrix called as decidua, which afterward becomes the maternal part of the placenta.

In Assisted reproduction, the key cause for implantation failure is the hatching disability of embryo. Presently, no research is available to distinguish the embryos which have the ability to hatch and grow into a healthy embryo. No hatching is a possible reason for pregnancy failure in many elderly women. In that case, zona pellucida can be disrupted by using laser assisted hatching technique to improve the pregnancy rate. Reviva Fertility Clinic & IVF Center In Chandigarh offers all the latest techniques which can treat various types of infertility.

For more information about infertility please visit our website www.revivaivf.com


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Why a trend from fresh to frozen embryo transfer?

Why a trend from fresh to frozen embryo transfer?

Whenever a sudden shift is made from fresh embryo transfer to frozen embryo transfer the couple usually have many queries in mind. So, let’s evaluate both and see pros and cons.

Fresh embryos transfer is undergoing ovarian hyper stimulation making of embryos and transferring resultant embryos to uterine cavity in same cycle. In frozen embryo transfer first two steps of controlled ovarian hyper stimulation and process of IVF/ICSI are same but the resultant embryos are frozen using vitrification techniques and not transferred in same cycle. They are thawed and then kept uterine cavity after preparing the uterine cavity.

In patients who are normal or hyper responders the frozen embryo transfers are known to have better results than the fresh embryo transfer . The reason can be that due to ovarian hyper stimulation and high levels of estrogen may have negative impacts on the endometrial receptivity. In some cycles another hormone called progesterone may also be raised, which again decreases embryo implantation rate. Whereas in frozen embryo transfer the body and uterus have already recovered from the impact of hormonal disturbance and hence more receptive.

Because of their reason in patient with PCOS the frozen embryo transfer is associated with higher live birth rate. It also reduces complications like ovarian hypertimulation in these patients.

Another reason where we make a sudden shift from fresh to frozen embryo transfer are when the ovarian stimulation part is good but the endometrial thickness fails to reach an optimal level.

So because of the above reasons we are moving towards more frozen transfer than fresh transfers in self cycle.

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What is Endometriosis?

This is a clinical entity where the uterine lining cells are present outside the uterus, usually, ovaries. The incidence is in reproductive age group.

This condition effects your chances of conceiving by decreasing number and quality of eggs, causing pelvic adhesions and hence tubal blockage toxic microenvironment and also effects endometrium receptivity. (2-10 % in women in general population and 20-30% in infertile group)

Endometriosis and Fertility: Understanding the Impact

Women with endometriosis are 5% less likely to continue naturally even in cases of mild endometriosis. In severe endometriosis the fertility decrease is much higher.

Now since endometriosis is an on-going process, so when diagnosed we tell the patient to plan early. Even after surgical removal of endometriotic cyst, the non visible endometriotic spots continue to release toxins which can effect your fertility. And if patient doesn’t take any treatment after surgery and doesn’t conceive within six months, the pre-surgical state may come again. So postsurgery aggressive treatment is required in cases of grade 3-4 and those with grade 1 and 2 are advised to plan early either naturally or IUI.

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